Company Operations by Product - Summary of Revenue (Details) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2018 USD ($)	Sep. 30, 2017 USD ($)	Sep. 30, 2018 USD ($) segment	Sep. 30, 2017 USD ($)
Segment Reporting [Abstract]
Number of operating segments (in segments) | segment			1
Segment Reporting Information [Line Items]
Total revenues	$ 19,826	$ 39,675	$ 82,349	$ 138,493
Bloxiverz
Segment Reporting Information [Line Items]
Total revenues	3,656	9,920	16,691	37,541
Vazculep
Segment Reporting Information [Line Items]
Total revenues	8,759	9,573	33,097	29,906
Akovaz
Segment Reporting Information [Line Items]
Total revenues	5,991	18,561	28,083	65,110
Noctiva
Segment Reporting Information [Line Items]
Total revenues	1,047	0	2,002	0
Other
Segment Reporting Information [Line Items]
Total revenues	373	1,093	2,230	5,452
Product sales
Segment Reporting Information [Line Items]
Total revenues	19,826	39,147	82,103	138,009
License revenue
Segment Reporting Information [Line Items]
Total revenues	$ 0	$ 528	$ 246	$ 484