UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF INCOME (LOSS) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017
Revenues:
Total revenues	$ 19,826	$ 39,675	$ 82,349	$ 138,493
Operating expenses:
Cost of products	3,120	3,790	13,224	12,253
Research and development expenses	11,402	8,095	33,243	22,093
Selling, general and administrative expenses	24,829	11,563	77,159	35,804
Intangible asset amortization	1,620	564	4,996	1,692
Gain - changes in fair value of related party contingent consideration	(7,115)	(9,906)	(17,036)	(30,107)
Restructuring costs	65	(549)	268	3,173
Total operating expenses	33,921	13,557	111,854	44,908
Operating (loss) income	(14,095)	26,118	(29,505)	93,585
Investment and other income, net	208	977	845	2,562
Interest expense	(3,000)	(263)	(7,577)	(789)
Other income - changes in fair value of related party payable	425	768	1,432	2,988
(Loss) income before income taxes	(16,462)	27,600	(34,805)	98,346
Income tax (benefit) provision	(691)	5,921	(3,360)	21,830
Net (loss) income	$ (15,771)	$ 21,679	$ (31,445)	$ 76,516
Net income (loss) per share - basic (in dollars per share)	$ (0.43)	$ 0.54	$ (0.84)	$ 1.87
Net income (loss) per share - diluted (in dollars per share)	$ (0.43)	$ 0.52	$ (0.84)	$ 1.81
Weighted average number of shares outstanding - basic (in shares)	36,904	40,061	37,410	40,839
Weighted average number of shares outstanding - diluted (in shares)	36,904	41,339	37,410	42,194
Product sales
Revenues:
Total revenues	$ 19,826	$ 39,147	$ 82,103	$ 138,009
License revenue
Revenues:
Total revenues	$ 0	$ 528	$ 246	$ 484