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Goodwill and Intangible Assets - Gross Value and Net Carrying Amount (Details) - USD ($)
$ in Thousands
Jun. 30, 2018
Dec. 31, 2017
Amortizable intangible assets:    
Gross Value $ 85,172 $ 106,072
Accumulated Amortization (14,210) (13,783)
Net Carrying Amount 70,962 92,289
Unamortizable intangible assets:    
Gross Value 18,491 18,491
Accumulated Amortization 0 0
Net Carrying Amount 18,491 18,491
Developed technology    
Amortizable intangible assets:    
Gross Value 0 4,300
Accumulated Amortization 0 (634)
Net Carrying Amount 0 3,666
Developed technology | Noctiva    
Amortizable intangible assets:    
Gross Value 73,111 73,111
Accumulated Amortization (4,186) (1,401)
Net Carrying Amount 68,925 71,710
Developed technology | Vazculep    
Amortizable intangible assets:    
Gross Value 12,061 12,061
Accumulated Amortization (10,024) (9,616)
Net Carrying Amount 2,037 2,445
Product marketing rights    
Amortizable intangible assets:    
Gross Value 0 16,600
Accumulated Amortization 0 (2,132)
Net Carrying Amount $ 0 $ 14,468