Goodwill and Intangible Assets - Gross Value and Net Carrying Amount (Details) - USD ($) $ in Thousands	Mar. 31, 2018	Dec. 31, 2017
Amortizable intangible assets:
Gross Value	$ 85,172	$ 106,072
Accumulated Amortization	(12,601)	(13,783)
Net Carrying Amount	72,571	92,289
Unamortizable intangible assets:
Gross Value	18,491	18,491
Accumulated Amortization	0	0
Net Carrying Amount	18,491	18,491
Developed technology
Amortizable intangible assets:
Gross Value	0	4,300
Accumulated Amortization	0	(634)
Net Carrying Amount	0	3,666
Developed technology | Noctiva
Amortizable intangible assets:
Gross Value	73,111	73,111
Accumulated Amortization	(2,781)	(1,401)
Net Carrying Amount	70,330	71,710
Developed technology | Vazculep
Amortizable intangible assets:
Gross Value	12,061	12,061
Accumulated Amortization	(9,820)	(9,616)
Net Carrying Amount	2,241	2,445
Product marketing rights
Amortizable intangible assets:
Gross Value	0	16,600
Accumulated Amortization	0	(2,132)
Net Carrying Amount	$ 0	$ 14,468