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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 FSdx86a4OTnY3tiH9Ux1Txd33NaaHRAb9/yV9eDb45wLCWNUGehbB6W7TgkC6I28
 5J0WIYrN7MlRNQ3vK84K1g==

<SEC-DOCUMENT>9999999995-06-002176.txt : 20061106
<SEC-HEADER>9999999995-06-002176.hdr.sgml : 20061106
<ACCEPTANCE-DATETIME>20061106001521
ACCESSION NUMBER:		9999999995-06-002176
CONFORMED SUBMISSION TYPE:	EFFECT
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20061103
DATE AS OF CHANGE:		20061106
EFFECTIVENESS DATE:		20061103

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MEDIVATION, INC.
		CENTRAL INDEX KEY:			0001011835
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				133863260
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		EFFECT
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-138057
		FILM NUMBER:		061188547

	BUSINESS ADDRESS:	
		STREET 1:		501 SECOND STREET
		STREET 2:		SUITE 211
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94107
		BUSINESS PHONE:		415-543-3470

	MAIL ADDRESS:	
		STREET 1:		501 SECOND STREET
		STREET 2:		SUITE 211
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94107

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ORION ACQUISITION CORP II
		DATE OF NAME CHANGE:	19960408
</SEC-HEADER>
<DOCUMENT>
<TYPE>EFFECT
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0101</schemaVersion>

    <submissionType>EFFECT</submissionType>

    <act>33</act>

    <testOrLive>LIVE</testOrLive>

    <effectiveData>
        <finalEffectivenessDispDate>2006-11-03</finalEffectivenessDispDate>
        <finalEffectivenessDispTime>16:30:00</finalEffectivenessDispTime>
        <form>S-3</form>
        <filer>
            <cik>0001011835</cik>
            <entityName>MEDIVATION, INC.</entityName>
            <fileNumber>333-138057</fileNumber>
        </filer>
    </effectiveData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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