Other Balance Sheet Items (Tables)

3 Months Ended

Mar. 31, 2016

Balance Sheet Related Disclosures [Abstract]

Schedule of Property and Equipment, Net

Property and equipment, net, consisted of the following:

	March 31, 2016			December 31, 2015
Leasehold improvements	$	22,615		$	19,074
Build-to-suit property		18,371			18,371
Computer equipment and software		17,300			16,083
Furniture and fixtures		6,014			5,714
Construction in progress		12,806			14,440
Laboratory equipment		1,447			748
		78,553			74,430
Less: Accumulated depreciation		(18,704	)		(16,288	)
Total	$	59,849		$	58,142

Components of Accounts Payable, Accrued Expenses and Other Current Liabilities

Accounts payable, accrued expenses and other current liabilities consisted of the following:

	March 31, 2016		December 31, 2015
Clinical and preclinical	$	45,635	$	48,975
Accounts payable		23,791		22,696
Payroll and payroll-related		15,988		29,215
Royalties payable		21,015		20,665
Accrued professional services and other current liabilities		15,566		14,282
Taxes payable		—		32,565
Other payable to licensor		—		17,500
Interest payable		—		305
Total	$	121,995	$	186,203