Build-to-Suit Lease Obligation - Additional Information (Detail) $ in Thousands	3 Months Ended	6 Months Ended		12 Months Ended
	Jun. 30, 2015 ft²	Jun. 30, 2016 USD ($) ft²	Jun. 30, 2015 USD ($) ft²	Dec. 31, 2015 USD ($) ft²	Mar. 31, 2016 USD ($)	Dec. 31, 2013 ft²
Build To Suit Lease Obligation [Line Items]
Operating lease | ft²		158,000
Amounts capitalized under build-to-suit lease transactions			$ 283
Area of property surrendered | ft²				8,000
Derecognized portion of build-to-suit asset			$ 3,241	$ 3,200
Derecognized portion of build-to-suit lease obligation				3,200
Build-to-suit building, historical cost					$ 18,400
Total build-to-suit lease obligation, including current and non-current portions		$ 17,400
Build-to-suit lease obligation, excluding current portion		$ 17,244		17,406
Laboratory Space [Member]
Build To Suit Lease Obligation [Line Items]
Operating lease | ft²	44,000		44,000			52,000
Lease expiry period		August 2024
Build to suit lease extension term	5 years
Build-to-suit Lease Property and Equipment [Member]
Build To Suit Lease Obligation [Line Items]
Amounts capitalized under build-to-suit lease transactions				14,500
Tenant Improvements [Member]
Build To Suit Lease Obligation [Line Items]
Amounts capitalized under build-to-suit lease transactions				3,600
Capitalized Interest Cost [Member]
Build To Suit Lease Obligation [Line Items]
Amounts capitalized under build-to-suit lease transactions				$ 3,500