Other Balance Sheet Items (Tables)

6 Months Ended

Jun. 30, 2016

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Schedule of Property and Equipment, Net

Property and equipment, net, consisted of the following:

	June 30, 2016			December 31, 2015
Leasehold improvements	$	26,658		$	19,074
Computer equipment and software		20,194			16,083
Build-to-suit property		18,371			18,371
Construction in progress		6,446			14,440
Furniture and fixtures		6,014			5,714
Laboratory equipment		4,472			748
		82,155			74,430
Less: Accumulated depreciation		(21,161	)		(16,288	)
Total	$	60,994		$	58,142

Accounts Payable, Accrued Expenses and Other Current Liabilities

Accounts payable, accrued expenses and other current liabilities consisted of the following:

	June 30, 2016		December 31, 2015
Clinical and preclinical	$	44,749	$	48,975
Accrued professional services and other current liabilities		24,893		14,282
Payroll and payroll-related		22,980		29,215
Royalties payable		22,740		20,665
Accounts payable		19,664		22,696
Taxes payable		—		32,565
Other payable to licensor		—		17,500
Interest payable		—		305
Total	$	135,026	$	186,203