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Collaboration Agreement - Schedule of Collaboration Revenue (Detail) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Sep. 30, 2015
Sep. 30, 2014
Organization, Consolidation and Presentation of Financial Statements [Abstract]        
Related to U.S. XTANDI net sales $ 156,501 $ 90,723 $ 417,731 $ 224,814
Related to ex-U.S. XTANDI net sales 33,599 15,522 74,957 31,245
Related to upfront and milestone payments 70,565 94,233 72,822 179,698
Collaboration revenue $ 260,665 $ 200,478 $ 565,510 $ 435,757