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Collaboration Agreement - Schedule of Potential Milestone Payments in Sales (Parenthetical) (Detail) - USD ($)
$ in Millions
3 Months Ended
Sep. 30, 2015
Dec. 31, 2014
Dec. 31, 2013
Organization, Consolidation and Presentation of Financial Statements [Abstract]      
Milestone payments earned $ 70.0 $ 50.0 $ 25.0