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Collaboration Agreement - Schedule of Collaboration Revenue (Detail) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2015
Jun. 30, 2014
Jun. 30, 2015
Jun. 30, 2014
Organization, Consolidation and Presentation of Financial Statements [Abstract]        
Related to U.S. XTANDI net sales $ 149,220 $ 71,866 $ 261,230 $ 134,091
Related to ex-U.S. XTANDI net sales 25,591 9,992 41,358 15,723
Related to upfront and milestone payments 846 66,232 2,257 85,465
Collaboration revenue $ 175,657 $ 148,090 $ 304,845 $ 235,279