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Selected Quarterly Financial Data (Tables)
 12 Months Ended
Dec. 31, 2013
Quarterly Financial Information Disclosure [Abstract]  
Selected Quarterly Financial Data

The following table presents the unaudited quarterly results of operations of the Company for the years ended December 31, 2013 and 2012, respectively. The unaudited financial information is prepared on the same basis as the audited consolidated financial statements. The Company’s operating results for any quarter are not necessarily indicative of results for any future quarters or for a full year. All share and per share amounts have been retroactively adjusted to reflect the Company’s September 21, 2012 two-for-one forward stock split.

 

     Quarters Ended  
     March 31,     June 30,     September 30,     December 31,  

2013:

         

Collaboration revenue

    $ 46,154      $ 70,149      $ 60,027      $ 96,612   

Operating expenses

    $ (68,476 )    $ (70,095 )    $ (68,025 )    $ (88,587 ) 

Income (loss) from operations

    $ (22,322 )    $ 54      $ (7,998 )    $ 8,025   

Net income (loss)

    $ (27,170 )    $ (4,898 )    $ (13,313 )    $ 2,768   

Basic net income (loss) per common share

    $ (0.36 )    $ (0.07 )    $ (0.18 )    $ 0.04   

Diluted net income (loss) per common share

    $ (0.36 )    $ (0.07 )    $ (0.18 )    $ 0.03   

Weighted-average common shares used in the calculation of basic net income (loss) per common share

      74,824        75,013        75,255        75,560   

Weighted-average common shares used in the calculation of diluted net income (loss) per common share

      74,824        75,013        75,255        79,912   

2012:

         

Collaboration revenue

    $ 36,825      $ 42,912      $ 64,798      $ 37,161   

Operating expenses

    $ (35,717 )    $ (43,887 )    $ (64,390 )    $ (63,916 ) 

Income (loss) from operations

    $ 1,108      $ (975 )    $ 408      $ (26,755 ) 

Net income (loss)

    $ 440      $ (5,500 )    $ (4,537 )    $ (31,660 ) 

Basic net income (loss) per common share

    $ 0.01      $ (0.08 )    $ (0.06 )    $ (0.43 ) 

Diluted net income (loss) per common share

    $ 0.01      $ (0.08 )    $ (0.06 )    $ (0.43 ) 

Weighted-average common shares used in the calculation of basic net income (loss) per common share

      71,907        72,770        73,697        74,489   

Weighted-average common shares used in the calculation of diluted net income (loss) per common share

      77,299        72,770        73,697        74,489