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Stockholders' Equity (Tables)
12 Months Ended
Dec. 31, 2013
Equity [Abstract]  
Summary of Stock Option Activity

The following table summarizes stock option activity for the year ended December 31, 2013:

 

     Number of
Options
    Weighted-
Average
Exercise Price
     Weighted-
Average
Remaining
Contractual
Term
(in years)
     Aggregate
Intrinsic
Value(1)
 

Outstanding at December 31, 2012

     7,038,291      $ 18.90         

Granted

     496,216      $ 51.06         

Exercised

     (793,756   $ 11.18         

Forfeited/expired

     (126,217   $ 22.59         
  

 

 

         

Outstanding at December 31, 2013

     6,614,534      $ 22.12         6.58       $ 275.8   
  

 

 

         

Vested and exercisable at December 31, 2013

     4,402,561      $ 14.85         5.63       $ 215.6   
  

 

 

         

 

(1) The aggregate intrinsic value is calculated as the pre-tax difference between the weighted-average exercise price of the underlying awards and the closing price per share of $63.82 of the Company’s common stock on December 31, 2013. The calculation excludes any awards with an exercise price higher than the closing price of the Company’s common stock on December 31, 2013. The amounts are presented in millions.
Schedule of Value of Options Vested and Exercised

Additional information regarding stock options is set forth below (in thousands, except per share data):

 

     Years Ended December 31,  
     2013      2012      2011  

Intrinsic value of options exercised

   $ 35,155       $ 116,867       $ 22,238   

Grant-date fair value of options vested

   $ 22,278       $ 10,795       $ 12,608   

Weighted-average grant-date fair value per share of options granted

   $ 30.39       $ 26.01       $ 6.88   
Summary of Restricted Stock Units

The following table summarizes restricted stock unit activity for the year ended December 31, 2013:

 

     Number of
Shares
    Weighted-
Average
Grant-Date
Fair Value
 

Unvested at December 31, 2012

     373,625      $ 39.06   

Granted

     143,939      $ 54.94   

Vested

     (188,139   $ 28.09   

Forfeited

     (18,078   $ 47.16   
  

 

 

   

Unvested at December 31, 2013

     311,347      $ 52.57   
  

 

 

   
Summary of Stock Appreciation Rights Activity

The following table summarizes stock appreciation rights activity for the year ended December 31, 2013:

 

     Number of
Rights
    Weighted-
Average
Exercise Price
     Weighted-
Average
Remaining
Contractual
Term
(in years)
     Aggregate
Intrinsic
Value(1)
 

Outstanding at December 31, 2012

     883,600      $ 23.91         

Granted

     —         —          

Exercised

     (37,442   $ 23.20         

Forfeited

     (40,042   $ 23.20         
  

 

 

         

Outstanding at December 31, 2013

     806,116      $ 23.98         8.05       $ 32.1   
  

 

 

         

Vested and exercisable at December 31, 2013

     395,519      $ 23.99         8.10       $ 15.8   
  

 

 

         

 

(1) The aggregate intrinsic value is calculated as the pre-tax difference between the weighted-average exercise price of the underlying awards and the closing price per share of $63.82 of the Company’s common stock on December 31, 2013. The calculation excludes any awards with an exercise price higher than the closing price of the Company’s common stock on December 31, 2013. The amounts are presented in millions.
Schedule of Black-Scholes Assumptions Used for Stock Options and Stock Appreciation Rights

The Black-Scholes assumptions used to estimate the fair value of stock options and stock appreciation rights were as follows:

 

     Years Ended December 31,  
     2013     2012     2011  

Expected volatility

     64-75     66-73     71-86

Expected term (in years)

     5.2-5.5        5.3-5.5        5.6-6.0   

Risk-free interest rate

     0.73-1.64     0.68-1.01     1.02-2.34

Expected dividend yield

     —         —         —    
Schedule of Black-Scholes Assumptions Used in Estimating Fair Value of Shares Issued under ESPP

The fair value of shares issued under the ESPP was estimated on the commencement date of the offering period using the Black-Scholes model and the following assumptions:

 

     Years Ended December 31,  
     2013     2012      2011  

Expected volatility

     45     —          —    

Expected term (in years)

     0.5        —          —    

Risk-free interest rate

     0.04     —          —    

Expected dividend yield

     —         —          —    
Schedule of Stock-Based Compensation Expense

Stock-based compensation expense was as follows:

 

     Years Ended December 31,  
     2013      2012      2011  

Stock-based compensation expense recognized as:

        

R&D expenses

   $ 16,503       $ 11,998       $ 8,090   

SG&A expenses

     20,575         11,680         5,795   
  

 

 

    

 

 

    

 

 

 

Total

   $ 37,078       $ 23,678       $ 13,885