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Property and Equipment, Net - Schedule of Property and Equipment, Net (Detail) (USD $)
In Thousands, unless otherwise specified
Mar. 31, 2013
Dec. 31, 2012
Property, Plant and Equipment [Line Items]    
Property and equipment, gross $ 19,163 $ 15,396
Less: Accumulated depreciation and amortization (2,691) (2,134)
Property and equipment, net 16,472 13,262
Leasehold improvements [Member]
   
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 9,080 9,057
Construction in progress [Member]
   
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 3,870 281
Computer equipment and software [Member]
   
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 3,111 3,166
Furniture and fixtures [Member]
   
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 2,858 2,648
Laboratory equipment [Member]
   
Property, Plant and Equipment [Line Items]    
Property and equipment, gross $ 244 $ 244