Consolidated Statements Of Operations (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended		9 Months Ended
	Sep. 30, 2012	Sep. 30, 2011	Sep. 30, 2012	Sep. 30, 2011
Collaboration revenue	$ 64,798	$ 14,940	$ 144,535	$ 45,448
Operating expenses:
Research and development	32,045	18,706	73,625	55,463
Selling, general and administrative	32,345	7,724	70,369	20,916
Total operating expenses	64,390	26,430	143,994	76,379
Income (loss) from operations	408	(11,490)	541	(30,931)
Other income (expense):
Interest expense	(4,840)		(10,113)
Interest income	57	19	140	69
Other income (expense), net	(154)	62	(169)	(370)
Total other income (expense), net	(4,937)	81	(10,142)	(301)
Net loss before income tax (expense) benefit	(4,529)	(11,409)	(9,601)	(31,232)
Income tax (expense) benefit	(8)	1,365	4	3,262
Net loss	$ (4,537)	$ (10,044)	$ (9,597)	$ (27,970)
Basic and diluted net loss per common share	$ (0.06)	$ (0.14)	$ (0.13)	$ (0.40)
Weighted average common shares used in the calculation of basic and diluted net loss per common share	73,697	69,818	72,794	69,642