Consolidated Statements Of Operations (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended		6 Months Ended
	Jun. 30, 2012	Jun. 30, 2011	Jun. 30, 2012	Jun. 30, 2011
Collaboration revenue	$ 42,912	$ 15,799	$ 79,737	$ 30,508
Operating expenses:
Research and development	21,550	19,139	41,580	36,757
Selling, general and administrative	22,337	7,036	38,024	13,192
Total operating expenses	43,887	26,175	79,604	49,949
Income (loss) from operations	(975)	(10,376)	133	(19,441)
Other income (expense):
Interest expense	(4,688)		(5,273)
Interest income	56	9	83	50
Other income (expense)	83	(99)	(15)	(432)
Total other income (expense), net	(4,549)	(90)	(5,205)	(382)
Net loss before income tax benefit	(5,524)	(10,466)	(5,072)	(19,823)
Income tax benefit	(24)	(992)	(12)	(1,897)
Net loss	$ (5,500)	$ (9,474)	$ (5,060)	$ (17,926)
Basic and diluted net loss per common share	$ (0.15)	$ (0.27)	$ (0.14)	$ (0.52)
Weighted average common shares used in the calculation of basic and diluted net loss per common share	36,385	34,888	36,169	34,776