Stockholders' Equity (Tables)

3 Months Ended

Mar. 31, 2012

Stockholders' Equity [Abstract]

Summary Of Stock Option Activity

	Number of Options			Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (in years)		Aggregate Intrinsic Value (1)
Outstanding at December 31, 2011		4,301,808		$	18.34
Granted		251,378		$	57.92
Exercised		(477,858	)	$	14.22
Forfeited		(26,088	)	$	26.19
Outstanding at March 31, 2012		4,049,240		$	21.24		6.99	$	216.6
Vested and exercisable at March 31, 2012		2,427,021		$	17.52		5.80	$	138.8

(1) The aggregate intrinsic value is calculated as the pre-tax difference between the exercise price of the underlying awards and the closing stock price per share of $74.72 of the Company's common stock on March 30, 2012. The amount is presented in millions.

Schedule Of Black-Scholes Assumptions Used For Stock Options

	Three Months Ended March 31,
	2012			2011
Risk-free interest rate		0.99-1.01	%		2.33-2.34	%
Estimated term (in years)		5.48			5.99
Estimated volatility		73	%		81	%
Estimated dividend yield		None			None
Weighted-average grant-date fair value per share of options granted	$	35.78		$	11.07

Summary Of Restricted Stock Units

	Number of Shares			Weighted- Average Grant-Date Fair Value
Unvested at December 31, 2011		101,617		$	14.35
Granted		32,903		$	46.39
Forfeited		(4,597	)	$	25.02
Unvested at March 31, 2012		129,923		$	22.08

Schedule Of Performance Share Awards

	Base Case Achievement		Upside Case Achievement
Performance shares eligible to be earned		20,835		41,666

Summary Of Stock Appreciation Rights Activity

	Number of Rights		Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (in years)		Aggregate Intrinsic Value (1)
Outstanding at December 31, 2011		262,800	$	48.79
Granted		193,700	$	46.39
Outstanding at March 31, 2012		456,500	$	47.77		9.72	$	12.3

(1) The aggregate intrinsic value is calculated as the pre-tax difference between the exercise price of the underlying awards and the closing stock price per share of $74.72 of the Company's common stock on March 30, 2012. The amount is presented in millions.

Schedule Of Black-Scholes Assumptions Used For Stock Appreciation Rights Awards

	Stock Appreciation Rights Granted During the Three Months Ended March 31, 2012			Remeasurement as of March 31, 2012
Risk-free interest rate		1.01	%		1.18	%
Estimated term (in years)		5.48			5.48
Estimated volatility		73	%		73	%
Estimated dividend yield		None			None

Schedule Of Stock-Based Compensation Expense

	Three months ended March 31,
	2012		2011
Stock-based compensation expense recognized as:
Research and development expense	$	2,437	$	2,070
Selling, general and administrative expense		1,899		1,544
Total	$	4,336	$	3,614