Collaboration Agreements (Deferred Revenue) (Details) (USD $) In Thousands, unless otherwise specified	Dec. 31, 2011	Dec. 31, 2010
Deferred revenue, Current	$ 59,762	$ 59,153
Deferred revenue, Long-term portion	83,509	141,507
Astellas [Member]
Deferred revenue, Current	23,747	23,138
Deferred revenue, Long-term portion	47,494	69,477
Pfizer [Member]
Deferred revenue, Current	36,015	36,015
Deferred revenue, Long-term portion	$ 36,015	$ 72,030

The carrying amount of consideration received or receivable as of the balance sheet date on potential earnings that were not recognized as revenue in conformity with GAAP, and which are expected to be recognized as such within one year or the normal operating cycle, if longer, including sales, license fees, and royalties, but excluding interest income.

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The noncurrent portion of deferred revenue amount as of balance sheet date. Deferred revenue is a liability related to a revenue producing activity for which revenue has not yet been recognized, and is not expected to be recognized in the next twelve months. Generally, an entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP.

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