AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON OCTOBER 15, 2002

                                                   COMMISSION FILE NO. 333-38110

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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                         POST-EFFECTIVE AMENDMENT NO. 1
                                       TO
                                    FORM S-8

                             REGISTRATION STATEMENT
                        UNDER THE SECURITIES ACT OF 1933

                              VISIBLE GENETICS INC.
             (Exact name of registrant as specified in its charter)

               ONTARIO                               98-0194462
  (State or other jurisdiction of       (I.R.S. Employer Identification Number)
  incorporation or organization)

                           700 BAY STREET, SUITE 1000
                                TORONTO, ONTARIO
                                 CANADA M5G 1Z6
                                 (416) 813-3240
               (Address, Including Zip Code, and Telephone Number,
        Including Area Code, of Registrant's Principal Executive Offices)

                         2000 EMPLOYEE SHARE OPTION PLAN
                            (Full title of the plan)

                                   ----------

                           WILMER, CUTLER & PICKERING
                                2445 M STREET, NW
                              WASHINGTON, DC 20037
                           ATTENTION: RICHARD W. CASS
                                 (202) 663-6000
           (Name, address, including zip code, and a telephone number,
                   including area code, of agent for service)

                                   ----------

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                          DEREGISTRATION OF SECURITIES

         A total of 1,000,000 common shares of Visible Genetics Inc., an Ontario
corporation (the "Registrant") were registered under the Securities Act of 1933,
as amended, by the filing and effectiveness of a Registration Statement on Form
S-8 (File No. 333-38110) (the "Registration Statement").

         The purpose of this Post-Effective Amendment No. 1 to the Registration
Statement is to deregister and remove from registration such portion of the
1,000,000 common shares previously registered on the Registration Statement that
have not been sold as of the date hereof. This action is due to the termination
of the offering contemplated by the Registration Statement upon consummation of
a transaction among the Registrant, Bayer Corporation, and 2014011 Ontario Inc.,
a wholly owned subsidiary of Bayer Corporation. Pursuant to that transaction,
2014011 Ontario Inc. acquired all the outstanding common shares and outstanding
Series A Convertible Preferred Shares of the Registrant and amalgamated with the
Registrant to form an amalgamated company ("Amalco"), which retained the
corporate name Visible Genetics Inc., under the Business Corporations Act
(Ontario). As a result of the transaction, Bayer Corporation owns all of the
outstanding common shares of Amalco, the unexercised options pursuant to which
common shares could be issued under the Registration Statement were canceled,
and Amalco is the successor by amalgamation to the Registrant. No other shares
of capital stock of Amalco are outstanding.


                                   SIGNATURES

         Pursuant to the requirements of the Securities Act of 1933, Visible
Genetics Inc, as successor by amalgamation, certifies that it has reasonable
grounds to believe that it meets all of the requirements for filing on Form S-8
and has duly caused this Post-Effective Amendment No. 1 to its Registration
Statement of Form S-8 (Registration No. 333-38110) to be signed on its behalf by
the undersigned, thereunto duly authorized, in the City of Toronto, Province of
Ontario, Canada, on the 15th day of October 2002.

                                                VISIBLE GENETICS INC.

                                                By: /s/ Peter C. Knueppel
                                                    -----------------------
                                                       Peter C. Knueppel
                                                       President



         Pursuant to the requirements of the Securities Act of 1933, this
Post-Effective Amendment No. 1 to the Registration Statement of Form S-8
(Registration No. 333-38110) has been signed below by the following persons in
the capacities and on the dates indicated.

Signature                    Title                             Date

/s/ Peter C. Knueppel        President (principal executive    October 15, 2002
- ------------------------     officer)
Peter C. Knueppel

/s/ Thomas J. Clarke         Chief Financial Officer           October 15, 2002
- ------------------------     (principal financial officer
Thomas J. Clarke             and principal accounting
                             officer)


/s/ Thomas Tithecott         Director                          October 15, 2002
- ------------------------
Thomas Tithecott


Authorized Representative in the United States:

WILMER, CUTLER & PICKERING                                     October 15, 2002

By: /s/ Richard W. Cass
    --------------------
      Richard W. Cass