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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 FpgC9VZ3g/7llFggVpdJcyojDTRgEbxjCoTbOvf2U+oDQ6oOL+e+J20nn1u5+Dd2
 UyPqLlo4vTVblTtUCSm5zg==

<SEC-DOCUMENT>0001209191-04-058655.txt : 20041220
<SEC-HEADER>0001209191-04-058655.hdr.sgml : 20041220
<ACCEPTANCE-DATETIME>20041220142047
ACCESSION NUMBER:		0001209191-04-058655
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20041216
FILED AS OF DATE:		20041220
DATE AS OF CHANGE:		20041220

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			OccuLogix, Inc.
		CENTRAL INDEX KEY:			0001299139
		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
		IRS NUMBER:				593434771
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		5280 SOLAR DRIVE, SUITE 100
		CITY:			MISSISSAUGA
		STATE:			A6
		ZIP:			L4W 5M8
		BUSINESS PHONE:		905-602-2020

	MAIL ADDRESS:	
		STREET 1:		5280 SOLAR DRIVE, SUITE 100
		CITY:			MISSISSAUGA
		STATE:			A6
		ZIP:			L4W 5M8

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			TLC VISION CORP
		CENTRAL INDEX KEY:			0001010610
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-SPECIALTY OUTPATIENT FACILITIES, NEC [8093]
		STATE OF INCORPORATION:			A6
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-51030
		FILM NUMBER:		041213710

	BUSINESS ADDRESS:	
		STREET 1:		5600 EXPLORER DRIVE
		STREET 2:		SUITE 301
		CITY:			MISSISSAUGA ONTARIO
		STATE:			A6
		ZIP:			00000
		BUSINESS PHONE:		3144346900

	MAIL ADDRESS:	
		STREET 1:		540 MARYVILLE CENTRE DR
		STREET 2:		-
		CITY:			ST LOUIS
		STATE:			MO
		ZIP:			63141

	FORMER NAME:	
		FORMER CONFORMED NAME:	TLC LASER CENTER INC
		DATE OF NAME CHANGE:	19960314
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>bay15029_tlc.xml
<DESCRIPTION>MAIN DOCUMENT DESCRIPTION
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2004-12-16</periodOfReport>

    <issuer>
        <issuerCik>0001299139</issuerCik>
        <issuerName>OccuLogix, Inc.</issuerName>
        <issuerTradingSymbol>RHEO</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001010610</rptOwnerCik>
            <rptOwnerName>TLC VISION CORP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>5280 SOLAR DRIVE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>MISSISSAUGA</rptOwnerCity>
            <rptOwnerState></rptOwnerState>
            <rptOwnerZipCode>L4W 5M8</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2004-12-16</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>2330184</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>12.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3686685</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2004-12-16</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>0</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>12.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>17788379</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>Shares owned by TLC Visiion (USA) Corporation, a wholly owned subsidiary</value>
                    <footnoteId id="F1"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <footnotes>
        <footnote id="F1">Shares owned by TLC Visiion (USA) Corporation, a wholly owned subsidiary</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Robert May, Secretary and General Counsel</signatureName>
        <signatureDate>2004-12-20</signatureDate>
    </ownerSignature>
</ownershipDocument>

</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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