Exhibit 23.1

            CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We  hereby  consent  to the  incorporation  by  reference  in this  Registration
Statement  on Form S-3 of our  report  dated  March  28,  2006  relating  to the
financial statements,  which appears in SIGA Technologies,  Inc.'s Annual Report
on Form 10-K for the year  ended  December  31,  2005.  We also  consent  to the
reference to us under the heading "Experts" in such Registration Statement.


PricewaterhouseCoopers LLP
New York, New York
November 16, 2006


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