Exhibit 23.1

                       CONSENT OF INDEPENDENT ACCOUNTANTS

We hereby consent to the incorporation by reference in this Amendment No. 1 to
Form S-3 of our report dated February 17, 2004 relating to the financial
statements, which appears in SIGA Technologies, Inc.'s Annual Report on Form
10-KSB for the year ended December 31, 2003. We also consent to the
incorporation by reference in this Amendment No. 1 to Form S-3 of our report
dated July 17, 2003 relating to the financial statements of Plexus Vaccine Inc.,
which appears in Amendment No. 1 to the Current Report on Form 8-K of SIGA
Technologies, Inc., dated May 23, 2003 (filed on July 22, 2003). We also consent
to the reference to us under the heading "Experts" in this Amendment No. 1 to
Form S-3.


                                         /s/ PRICEWATERHOUSECOOPERS LLP

New York, New York
April 20, 2004