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Financial Information by Quarter
 12 Months Ended
Dec. 31, 2011
Financial Information by Quarter (unaudited) [Abstract]  
Quarterly Financial Information [Text Block]
Financial Information By Quarter (Unaudited)
 
Three Months Ended
2011
March 31
 
June 30
 
September 30
 
December 31
 
(in thousands, except for per share data)
Revenues
$
1,697

 
$
2,491

 
$
3,578

 
$
4,960

Selling, general and administrative
4,250

 
9,351

 
3,969

 
6,362

Research and development
3,566

 
3,835

 
5,170

 
5,796

Patent preparation fees
342

 
413

 
482

 
571

Operating loss
(6,461
)
 
(11,108
)
 
(6,043
)
 
(7,769
)
Net income (loss)
(4,701
)
 
23,842

 
210

 
(5,757
)
Earnings (loss) per share: basic
$
(0.09
)
 
$
0.47

 
$
—

 
$
(0.11
)
Earnings (loss) per share: diluted
$
(0.09
)
 
$
0.44

 
$
—

 
$
(0.11
)
Market price range for common stock
 
 
 
 
 
 
 
High
$
15.66

 
$
15.40

 
$
9.95

 
$
3.58

Low
$
10.66

 
$
9.53

 
$
2.61

 
$
1.78

 
 
 
 
 
 
 
 
 
Three Months Ended
2010
March 31
 
June 30
 
September 30
 
December 31
 
(in thousands, except for per share data)
Revenues
$
5,075

 
$
4,447

 
$
6,632

 
$
3,062

Selling, general and administrative
1,969

 
2,234

 
1,389

 
2,539

Research and development
5,827

 
4,930

 
7,420

 
4,482

Patent preparation fees
320

 
306

 
235

 
288

Operating loss
(3,041
)
 
(3,023
)
 
(2,412
)
 
(4,246
)
Net loss
(4,937
)
 
(5,251
)
 
(4,430
)
 
(13,577
)
Net loss per share: basic and diluted
$
(0.11
)
 
$
(0.12
)
 
$
(0.10
)
 
$
(0.29
)
Market price range for common stock
 
 
 
 
 
 
 
High
$
7.68

 
$
8.06

 
$
9.27

 
$
14.38

Low
$
5.50

 
$
6.03

 
$
6.99

 
$
7.76