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SIGNIFICANT ACCOUNTING POLICIES (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended
Jul. 02, 2021
USD ($)
$ / shares
shares
May 13, 2021
USD ($)
Feb. 17, 2021
USD ($)
$ / shares
shares
Feb. 10, 2021
USD ($)
Jul. 23, 2018
USD ($)
Oct. 19, 2017
USD ($)
Oct. 31, 2015
Jun. 30, 2021
USD ($)
agreement
$ / shares
shares
Jun. 30, 2020
$ / shares
shares
Jun. 30, 2021
USD ($)
agreement
$ / shares
shares
Jun. 30, 2020
$ / shares
shares
Dec. 31, 2020
USD ($)
Significant Accounting Policies [Line Items]                        
Number of shares issued (in shares) | shares     8,749,999                  
Common Stock, Par or Stated Value Per Share | $ / shares               $ 0.001 $ 0.001 $ 0.001 $ 0.001  
Gross proceeds     $ 40,200             $ 8,575    
Shares Issued, Price Per Share | $ / shares     $ 4.60                  
Convertible Debt, Current               $ 56,355   $ 56,355   $ 54,427
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount | shares               25,874,641 25,997,289 26,322,164 18,445,764  
ATM Shares                        
Significant Accounting Policies [Line Items]                        
Number of shares issued (in shares) | shares 3,296,123                      
Common Stock, Par or Stated Value Per Share | $ / shares $ 0.001                      
Sale of stock, maximum offering price $ 20,000                      
Gross proceeds $ 13,800                      
2021 Notes [Member] | Convertible Notes Payable [Member]                        
Significant Accounting Policies [Line Items]                        
Interest rate (as a percent)               7.50%   7.50%    
Amended Pfizer Agreement [Member] | Protalix Bio Therapeutics Incorporation [Member] | Brazil [Member]                        
Significant Accounting Policies [Line Items]                        
Collaborative Arrangement Revenues and Expenses Sharing Percentage             100.00%          
Chiesi Agreements [Member]                        
Significant Accounting Policies [Line Items]                        
Revenue, Performance Obligation, Number | agreement               2   2    
Chiesi US Agreement [Member]                        
Significant Accounting Policies [Line Items]                        
Additional Amounts Payable To Cover Development Costs         $ 20,000              
Maximum Entitlement Of Development Costs To Cover Per Year         7,500              
Additional Amount Payable For Achievement Of Regulatory And Commercial Milestones         $ 760,000              
Chiesi US Agreement [Member] | Minimum [Member]                        
Significant Accounting Policies [Line Items]                        
Payment On Net Sales Percentage         15.00%              
Chiesi US Agreement [Member] | Maximum                        
Significant Accounting Policies [Line Items]                        
Payment On Net Sales Percentage         40.00%              
Chiesi Ex US Agreement [Member]                        
Significant Accounting Policies [Line Items]                        
Additional Amounts Payable To Cover Development Costs           $ 25,000            
Maximum Entitlement Of Development Costs To Cover Per Year           10,000            
Agreement Amendment Payment Receivable   $ 10,000                    
Change In Amount Receivable For Achievement Of Regulatory And Commercial Milestones   $ 25,000                    
Additional Amount Payable For Achievement Of Regulatory And Commercial Milestones           $ 320,000            
Chiesi Ex US Agreement [Member] | Minimum [Member]                        
Significant Accounting Policies [Line Items]                        
Payment On Net Sales Percentage           15.00%            
Chiesi Ex US Agreement [Member] | Maximum                        
Significant Accounting Policies [Line Items]                        
Payment On Net Sales Percentage           35.00%            
SarcoMed USA, Inc. Agreement [Member]                        
Significant Accounting Policies [Line Items]                        
License Agreement, Initial Cash Payment       $ 3,500                
Term to sign supply agreement       60 days                
Chiesi US Agreement and Chiesi Ex US Agreement [Member]                        
Significant Accounting Policies [Line Items]                        
Upfront Nonrefundable Non-Creditable Payment Receivable         $ 25,000 $ 25,000