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CONSOLIDATED STATEMENTS OF CHANGES IN CAPITAL DEFICIENCY - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Beginning balance $ (70,322) $ (52,881) $ (29,457)
Issuance of common stock and warrants, net of issuance cost 41,343    
Issuance of common stock under the Sales Agreement, net 4,867    
Share-based compensation related to stock options 2,264 835 498
Share-based compensation related to restricted stock award 862   16
Convertible note conversions     1,369
Convertible note payment     1,150
Exercise of warrants 472    
Net loss (6,523) (18,276) (26,457)
Ending balance (27,037) (70,322) (52,881)
Common Stock [Member]      
Beginning balance $ 15 $ 15 $ 14
Beginning balance (in shares) 14,838,213 14,838,213 14,372,880
Issuance of common stock and warrants, net of issuance cost $ 18    
Issuance of common stock and warrants, net of issuance cost (in shares) 17,604,423    
Issuance of common stock under the Sales Agreement, net $ 1    
Issuance of common stock under the Sales Agreement, net (in shares) 1,428,571    
Share-based compensation related to restricted stock award $ 1    
Share-based compensation related to restricted stock award (in shares) 694,073   2,990
Convertible note conversions (in shares)     200,997
Convertible note payment     $ 1
Convertible note payment (in shares)     261,346
Exercise of warrants (in shares) 200,000    
Ending balance $ 35 $ 15 $ 15
Ending balance (in shares) 34,765,280 14,838,213 14,838,213
Additional Paid-in Capital [Member]      
Beginning balance $ 270,492 $ 269,657 $ 266,625
Issuance of common stock and warrants, net of issuance cost 41,325    
Issuance of common stock under the Sales Agreement, net 4,866    
Share-based compensation related to stock options 2,264 835 498
Share-based compensation related to restricted stock award 861   16
Convertible note conversions     1,369
Convertible note payment     1,149
Exercise of warrants 472    
Ending balance 320,280 270,492 269,657
Accumulated Deficit [Member]      
Beginning balance (340,829) (322,553) (296,096)
Net loss (6,523) (18,276) (26,457)
Ending balance $ (347,352) $ (340,829) $ (322,553)