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SIGNIFICANT ACCOUNTING POLICIES (Narrative) (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended
Jul. 23, 2018
Oct. 19, 2017
Mar. 31, 2019
Mar. 31, 2018
Jan. 01, 2019
Dec. 31, 2018
Oct. 31, 2015
Significant Accounting Policies [Line Items]              
Common Stock, Par or Stated Value Per Share     $ 0.001 $ 0.001      
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount     78,202,020 73,800,491      
Operating Lease, Right-of-Use Asset     $ 5,844   $ 5,900 $ 0  
Operating Lease, Liability     $ 5,755   $ 5,700    
Amended Pfizer Agreement [Member] | Protalix Bio Therapeutics Incorporation [Member] | Brazil [Member]              
Significant Accounting Policies [Line Items]              
Collaborative Arrangement Revenues and Expenses Sharing Percentage             100.00%
Chiesi US Agreement [Member]              
Significant Accounting Policies [Line Items]              
Upfront Nonrefundable Noncreditable Payment Receivable $ 25,000            
Additional Amounts Payable To Cover Development Costs 20,000            
Maximum Entitlement Of Development Costs To Cover Per Year 7,500            
Additional AmountPayable For Achievement Of Regulatory And Commercial Milestones $ 760,000            
Chiesi US Agreement [Member] | Minimum [Member]              
Significant Accounting Policies [Line Items]              
Payment On Net Sales Percentage 15.00%            
Chiesi US Agreement [Member] | Maximum [Member]              
Significant Accounting Policies [Line Items]              
Payment On Net Sales Percentage 40.00%            
Chiesi Ex US Agreement [Member]              
Significant Accounting Policies [Line Items]              
Upfront Nonrefundable Noncreditable Payment Receivable   $ 25,000          
Maximum Entitlement Of Development Costs To Cover Per Year   10,000          
Additional AmountPayable For Achievement Of Regulatory And Commercial Milestones   $ 320,000          
Chiesi Ex US Agreement [Member] | Minimum [Member]              
Significant Accounting Policies [Line Items]              
Payment On Net Sales Percentage   15.00%          
Chiesi Ex US Agreement [Member] | Maximum [Member]              
Significant Accounting Policies [Line Items]              
Payment On Net Sales Percentage   35.00%