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PROPERTY AND EQUIPMENT (Details) (USD $)
In Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Property, Plant and Equipment [Line Items]      
Property, Plant and Equipment, Gross $ 32,736us-gaap_PropertyPlantAndEquipmentGross $ 32,030us-gaap_PropertyPlantAndEquipmentGross  
Less - accumulated depreciation and amortization (21,454)us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment (18,319)us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment  
Property, Plant and Equipment, Net, Total 11,282us-gaap_PropertyPlantAndEquipmentNet 13,711us-gaap_PropertyPlantAndEquipmentNet  
Depreciation 3,140us-gaap_Depreciation 3,539us-gaap_Depreciation 3,692us-gaap_Depreciation
Laboratory Equipment [Member]      
Property, Plant and Equipment [Line Items]      
Property, Plant and Equipment, Gross 15,138us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= plx_LaboratoryEquipmentMember
14,858us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= plx_LaboratoryEquipmentMember
 
Furniture And Computer Equipment [Member]      
Property, Plant and Equipment [Line Items]      
Property, Plant and Equipment, Gross 2,154us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= plx_FurnitureAndComputerEquipmentMember
2,074us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= plx_FurnitureAndComputerEquipmentMember
 
Leasehold Improvements [Member]      
Property, Plant and Equipment [Line Items]      
Property, Plant and Equipment, Gross 15,427us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_LeaseholdImprovementsMember
15,070us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_LeaseholdImprovementsMember
 
Equipment Under Construction [Member]      
Property, Plant and Equipment [Line Items]      
Property, Plant and Equipment, Gross $ 17us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= plx_EquipmentUnderConstructionMember
$ 28us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= plx_EquipmentUnderConstructionMember