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SIGNIFICANT ACCOUNTING POLICIES (Details) (USD $)
3 Months Ended 12 Months Ended 1 Months Ended
Dec. 31, 2009
Dec. 31, 2014
item
Dec. 31, 2013
Dec. 31, 2012
Jun. 18, 2013
Significant Accounting Policies [Line Items]          
Number of Subsidiaries   2plx_NumberOfSubsidiaries      
Pfizer Agreement, upfront payment received $ 60,000,000us-gaap_ProceedsFromCollaborators        
Common stock, par value per share   $ 0.001us-gaap_CommonStockParOrStatedValuePerShare $ 0.001us-gaap_CommonStockParOrStatedValuePerShare    
Options to purchase common stock not included in diluted LPS because the effect would be anti-dilutive   18,850,724us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount 10,675,304us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount 7,280,469us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount  
Revenues   13,651,000us-gaap_Revenues 10,479,000us-gaap_Revenues 34,870,000us-gaap_Revenues  
Protalix Ltd. [Member]          
Significant Accounting Policies [Line Items]          
Supply commitment for entitled rights to be received         280,000,000plx_PurchaseAmountToBeSatisfiedToReceiveEntitledRights
/ dei_LegalEntityAxis
= us-gaap_SubsidiariesMember
License and supply agreement potential future payment         12,500,000plx_LicenseAndSupplyAgreementPotentialFuturePaymentBasedOnNetProfits
/ dei_LegalEntityAxis
= us-gaap_SubsidiariesMember
Supply commitment per year         40,000,000plx_SupplyCommitmentPerYear
/ dei_LegalEntityAxis
= us-gaap_SubsidiariesMember
Protalix Ltd. [Member] | Revenues from sale of products [Member]          
Significant Accounting Policies [Line Items]          
Revenues   3,500,000us-gaap_Revenues
/ dei_LegalEntityAxis
= us-gaap_SubsidiariesMember
/ plx_SupplementalInformationRevenueAxis
= us-gaap_SalesRevenueGoodsNetMember
     
Protalix Bio Therapeutics Inc. [Member]          
Significant Accounting Policies [Line Items]          
Pfizer Agreement, future revenues and expense sharing percentage   40.00%plx_CollaborativeArrangementProfitSharePercentage
/ us-gaap_TypeOfArrangementAxis
= plx_ProtalixBioTherapeuticsIncorporationMember
     
Pfizer Incorporation [Member]          
Significant Accounting Policies [Line Items]          
Pfizer Agreement, future revenues and expense sharing percentage   60.00%plx_CollaborativeArrangementProfitSharePercentage
/ us-gaap_TypeOfArrangementAxis
= plx_PfizerIncorporationMember
     
Upon FDAApproval [Member]          
Significant Accounting Policies [Line Items]          
Pfizer Agreement, milestone payment amount   $ 30,000,000plx_CollaborativeArrangementMilestonePaymentAmount
/ us-gaap_StatementScenarioAxis
= plx_UponFDAApprovalMember