<SEC-DOCUMENT>0001104659-22-077371-index.html : 20220705
<SEC-HEADER>0001104659-22-077371.hdr.sgml : 20220705
<ACCEPTANCE-DATETIME>20220705163059
ACCESSION NUMBER:		0001104659-22-077371
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20220630
FILED AS OF DATE:		20220705
DATE AS OF CHANGE:		20220705

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Ben Zvi Shmuel
		CENTRAL INDEX KEY:			0001935668

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-33357
		FILM NUMBER:		221065392

	MAIL ADDRESS:	
		STREET 1:		2 SNUNIT STREET
		STREET 2:		SCIENCE PARK, #455
		CITY:			CARMIEL
		STATE:			L3
		ZIP:			2161401

	FORMER NAME:	
		FORMER CONFORMED NAME:	Zvi Shmuel Ben
		DATE OF NAME CHANGE:	20220628

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Protalix BioTherapeutics, Inc.
		CENTRAL INDEX KEY:			0001006281
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				650643773
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		2 UNIVERSITY PLAZA
		STREET 2:		SUITE 100
		CITY:			HACKENSACK
		STATE:			NJ
		ZIP:			07601
		BUSINESS PHONE:		201-696-9345

	MAIL ADDRESS:	
		STREET 1:		2 UNIVERSITY PLAZA
		STREET 2:		SUITE 100
		CITY:			HACKENSACK
		STATE:			NJ
		ZIP:			07601

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ORTHODONTIX INC
		DATE OF NAME CHANGE:	19980422

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	EMBASSY ACQUISITION CORP
		DATE OF NAME CHANGE:	19960124
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>tm2220369-2_3seq1.xml
<DESCRIPTION>OWNERSHIP DOCUMENT
<TEXT>
Document 1 - file: tm2220369-2_3seq1.html

Document 1 - RAW XML: tm2220369-2_3seq1.xml

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24.1
<SEQUENCE>2
<FILENAME>tm2220369d2_ex24-1.htm
<DESCRIPTION>EXHIBIT 24.1
<TEXT>
Document 2 - file: tm2220369d2_ex24-1.htm

</DOCUMENT>
</SEC-DOCUMENT>