SIGNIFICANT ACCOUNTING POLICIES (Details) - USD ($) $ / shares in Units, $ in Thousands	1 Months Ended		3 Months Ended		9 Months Ended
	Jul. 23, 2018	Oct. 19, 2017	Sep. 30, 2019	Sep. 30, 2018	Sep. 30, 2019	Sep. 30, 2018	Jan. 01, 2019	Dec. 31, 2018	Dec. 31, 2017	Oct. 31, 2015
Significant Accounting Policies [Line Items]
Common Stock, Par or Stated Value Per Share			$ 0.001	$ 0.001	$ 0.001	$ 0.001
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount			78,547,287	73,280,977	78,269,464	73,310,911
Retained Earnings (Accumulated Deficit)			$ 341,000		$ 341,000
Cash and Cash Equivalents, at Carrying Value			21,442	$ 41,868	$ 21,442	$ 41,868		$ 37,808	$ 51,163
Lease, Practical Expedients, Package [true false]					true
Operating Lease, Right-of-Use Asset			5,764		$ 5,764		$ 5,900	$ 0
Operating Lease, Liability			5,754		5,754		$ 5,700
2021 Notes [Member]
Significant Accounting Policies [Line Items]
Long-term Debt, Gross			$ 57,900		$ 57,900
Debt Instrument, Interest Rate, Stated Percentage			7.50%		7.50%
Maintain of Minimum Cash Balance			$ 7,500		$ 7,500
Amended Pfizer Agreement [Member] | Protalix Bio Therapeutics Incorporation [Member] | Brazil [Member]
Significant Accounting Policies [Line Items]
Collaborative Arrangement Revenues and Expenses Sharing Percentage										100.00%
Chiesi US Agreement [Member]
Significant Accounting Policies [Line Items]
Upfront Nonrefundable Non-Creditable Payment Receivable	$ 25,000
Additional Amounts Payable To Cover Development Costs	20,000
Maximum Entitlement Of Development Costs To Cover Per Year	7,500
Additional Amount Payable For Achievement Of Regulatory And Commercial Milestones	$ 760,000
Chiesi US Agreement [Member] | Minimum [Member]
Significant Accounting Policies [Line Items]
Payment On Net Sales Percentage	15.00%
Chiesi US Agreement [Member] | Maximum [Member]
Significant Accounting Policies [Line Items]
Payment On Net Sales Percentage	40.00%
Chiesi Ex US Agreement [Member]
Significant Accounting Policies [Line Items]
Upfront Nonrefundable Non-Creditable Payment Receivable		$ 25,000
Additional Amounts Payable To Cover Development Costs		25,000
Maximum Entitlement Of Development Costs To Cover Per Year		10,000
Additional Amount Payable For Achievement Of Regulatory And Commercial Milestones		$ 320,000
Chiesi Ex US Agreement [Member] | Minimum [Member]
Significant Accounting Policies [Line Items]
Payment On Net Sales Percentage		15.00%
Chiesi Ex US Agreement [Member] | Maximum [Member]
Significant Accounting Policies [Line Items]
Payment On Net Sales Percentage		35.00%