EXHIBIT 32.1

CERTIFICATION OF CHIEF EXECUTIVE OFFICER AND CHIEF FINANCIAL OFFICER

PURSUANT TO

18 U.S.C. SECTION 1350,

AS ADOPTED PURSUANT TO

SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Quarterly Report of IRIDEX Corporation (the "Company") on Form 10-Q for the quarter ending July 2, 2005, as filed with the Securities and Exchange Commission on the date hereof (the "Report"), Barry G. Caldwell, Chief Executive Officer, and Larry Tannenbaum, Chief Financial Officer, of the Company, each certify, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that:

(1) The Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

(2) The information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of the Company.

Date: August 16, 2005
	By: /s/ BARRY G. CALDWELL
	Name: Barry G. Caldwell
	Title: President and Chief Executive Officer
	(Principal Executive Officer)
Date: August 16, 2005
	By: /s/ LARRY TANNENBAUM
	Name: Larry Tannenbaum
	Title: Chief Financial Officer and Vice President, Administration
	(Principal Financial and Accounting Officer)

35