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Stockholders' Equity and Equity Compensation Plans - Summary of Unvested Restricted Common Stock Activity (Details) - Restricted common stock - $ / shares
shares in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2022
Shares    
Shares, Unvested awards, beginning balance 1,265 1,206
Shares, Awards granted 17 553
Shares, Awards forfeited/cancelled (67) (162)
Shares, Awards vested (24) (406)
Shares, Unvested awards, ending balance 1,191 1,191
Weighted-Average Grant Date Fair Value    
Weighted-Average Grant Date Fair Value, Unvested awards, beginning balance $ 53.27 $ 45.22
Weighted-Average Grant Date Fair Value, Awards granted 57.02 63.41
Weighted-Average Grant Date Fair Value, Awards forfeited/cancelled 56.07 51.90
Weighted-Average Grant Date Fair Value, Awards vested 54.72 44.50
Weighted-Average Grant Date Fair Value, Unvested awards, ending balance $ 53.22 $ 53.22