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STOCK-BASED COMPENSATION - Equity Instruments Other Than Options - Additional Information (Details) - USD ($)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Compensation expense $ 0 $ 0 $ 0
Fair value of shares withheld for tax withholding obligations $ 11,620,000 $ 9,432,000 $ 4,871,000
Restricted Stock Units (RSUs) [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Weighted average grant-date fair value of restricted stock awards and units fully vested (in dollars per share) $ 115.48 $ 116.58 $ 53.85
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value $ 8,100,000 $ 8,300,000 $ 5,400,000
Grants in period (shares) 51,968    
Restricted Stock Units (RSUs) [Member] | Research and Development Expense [Member] | Non Employee Members of Scientific Advisory Board [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Compensation expense $ 64,000 $ 976,000 $ 242,000
Restricted Stock [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Weighted average grant-date fair value of restricted stock awards and units fully vested (in dollars per share) $ 122.15 $ 83.25 $ 65.37
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value $ 17,700,000 $ 14,800,000 $ 8,600,000
Shares withheld for employee taxes (shares) 86,679 89,661 84,135
Shares withheld for employee taxes $ 9,200,000 $ 7,800,000 $ 4,500,000
Grants in period (shares) 2,456    
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized $ 19,400,000    
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition 1 year 10 months 2 days    
Restricted Stock [Member] | Selling, General and Administrative Expense [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Compensation expense $ 7,600,000 8,500,000 6,600,000
Restricted Stock [Member] | Manufacturing Expense [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Compensation expense 758,000 443,000 1,100,000
Restricted Stock [Member] | Research and Development Expense [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Compensation expense $ 2,000,000 $ 1,600,000 $ 1,700,000
Performance Shares [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Weighted average grant-date fair value of restricted stock awards and units fully vested (in dollars per share) $ 119.62 $ 105.65 $ 58.46
Grants in period (shares) 40,601 24,664 25,045
Shares withheld for tax withholding obligations (in shares) 25,208 19,217  
Fair value of shares withheld for tax withholding obligations $ 2,900,000 $ 1,600,000  
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized $ 1,400,000    
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition 1 year 6 months 21 days    
Performance Shares [Member] | Performance-Based Vesting Requirement [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Grants in period (shares) 6,022 7,817 12,520
Performance Shares [Member] | Market-Based Vesting Requirement [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Grants in period (shares) 6,025 7,821 12,525
Performance Shares [Member] | Company Performance-Based Vesting Requirement [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Grants in period (shares) 28,554 9,026  
Performance Shares [Member] | Selling, General and Administrative Expense [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Compensation expense $ 1,300,000 $ 1,200,000 $ 1,300,000
Performance Shares [Member] | Manufacturing Expense [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Compensation expense 141,000 119,000 133,000
Performance Shares [Member] | Research and Development Expense [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Compensation expense $ 330,000 $ 276,000 $ 356,000