CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2017	Sep. 30, 2016
CASH FLOWS FROM OPERATING ACTIVITIES:
Net income	$ 71,072	$ 22,251
Adjustments to reconcile net income to net cash provided by operating activities:
Amortization of deferred revenue	(7,206)	(5,281)
Depreciation	3,638	3,002
Amortization of intangibles	16,485	11,039
Amortization of premium and discount on investments, net	(2,055)	(1,316)
Stock-based compensation to employees	8,467	8,231
Stock-based compensation to Board of Directors and Scientific Advisory Board	1,890	1,273
Change in earnout liability recorded for Adesis acquisition	509
Deferred income tax expense	6,804	4,726
Retirement plan expense	3,214	3,004
Decrease (increase) in assets:
Accounts receivable	(18,262)	3,723
Inventory	(15,419)	(3,249)
Other current assets	(2,835)	(4,977)
Other assets	(40)	(249)
Increase (decrease) in liabilities:
Accounts payable and accrued expenses	3,904	(5,134)
Other current liabilities	(768)	(5)
Deferred revenue	1,863	3,296
Net cash provided by operating activities	71,261	40,334
CASH FLOWS FROM INVESTING ACTIVITIES:
Purchases of property and equipment	(23,221)	(4,361)
Purchases of intangibles		(95,989)
Purchase of business, net of cash acquired		(33,163)
Purchases of investments	(456,264)	(380,260)
Proceeds from sale of investments	351,024	434,683
Net cash used in investing activities	(128,461)	(79,090)
CASH FLOWS FROM FINANCING ACTIVITIES:
Proceeds from issuance of common stock	529	317
Proceeds from the exercise of common stock options	29	182
Payment of withholding taxes related to stock-based compensation to employees	(9,330)	(4,840)
Cash dividends paid	(4,240)
Net cash used in financing activities	(13,012)	(4,341)
DECREASE IN CASH AND CASH EQUIVALENTS	(70,212)	(43,097)
CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD	139,365	97,513
CASH AND CASH EQUIVALENTS, END OF PERIOD	$ 69,153	$ 54,416