CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015
CASH FLOWS FROM OPERATING ACTIVITIES:
Net income (loss)	$ 22,251	$ (3,410)
Adjustments to reconcile net income (loss) to net cash provided by operating activities:
Amortization of deferred revenue	(5,281)	(7,031)
Depreciation	3,002	2,223
Amortization of intangibles	11,039	8,249
Inventory write-down		33,000
Amortization of premium and discount on investments, net	(1,316)	(479)
Stock-based compensation to employees	8,231	6,759
Stock-based compensation to Board of Directors and Scientific Advisory Board	1,273	818
Deferred income tax benefit	4,726	4,291
Retirement plan benefit expense	3,004	2,433
Decrease (increase) in assets, net of effect of acquisition:
Accounts receivable	3,723	(6,275)
Inventory	(3,249)	(9,579)
Other current assets	(4,977)	(167)
Other assets	(249)	193
Increase (decrease) in liabilities, net of effect of acquisition:
Accounts payable and accrued expenses	(5,134)	1,192
Other current liabilities	(5)	(7)
Deferred revenue	3,296	48,411
Net cash provided by operating activities	40,334	80,621
CASH FLOWS FROM INVESTING ACTIVITIES:
Purchases of property and equipment	(4,361)	(4,650)
Purchase of intangibles	(95,989)
Purchase of business, net of cash acquired	(33,163)
Purchases of investments	(380,260)	(453,672)
Proceeds from sale of investments	434,683	425,660
Net cash used in investing activities	(79,090)	(32,662)
CASH FLOWS FROM FINANCING ACTIVITIES:
Proceeds from issuance of common stock	317	263
Proceeds from the exercise of common stock options	182	1,629
Payment of withholding taxes related to stock-based compensation to employees	(4,840)	(5,313)
Net cash used in financing activities	(4,341)	(3,421)
(DECREASE) INCREASE IN CASH AND CASH EQUIVALENTS	(43,097)	44,538
CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD	97,513	45,418
CASH AND CASH EQUIVALENTS, END OF PERIOD	54,416	$ 89,956
Earnout liability recorded for Adesis acquisition	$ 1,510