Face (par) amount of debt instrument at time of issuance.

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Fair value portion of debt instrument payable, including, but not limited to, notes payable and loans payable.

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Contractual interest rate for funds borrowed, under the debt agreement.

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The amount of net income or loss for the period per each share in instances when basic and diluted earnings per share are the same amount and reported as a single line item on the face of the financial statements. Basic earnings per share is the amount of net income or loss for the period per each share of common stock or unit outstanding during the reporting period. Diluted earnings per share includes the amount of net income or loss for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.

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Amount of transfers of assets measured on a recurring basis out of Level 1 of the fair value hierarchy into Level 2.

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Amount of transfers of assets measured on a recurring basis out of Level 2 of the fair value hierarchy into Level 1.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Amount of gain (loss) recognized on the income statement for financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing.

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Amount of sales of financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing.

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Amount of transfers of financial instrument classified as a liability into (out of) level 3 of the fair value hierarchy.

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Fair value of financial instrument classified as a liability measured using unobservable inputs that reflect the entity's own assumption about the assumptions market participants would use in pricing.

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CASH, CASH EQUIVALENTS AND SHORT-TERM INVESTMENTS - LEVEL 3 (Details) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015	Sep. 09, 2014
Changes in fair value of all financial liabilities measured at fair value on a recurring basis
Earnings Per Share, Basic and Diluted	$ (1.63)	$ (1.45)	$ (1.26)
Fair value transfers between hierarchy levels 1 and 2
Transfers of assets from Level 1 to Level 2	$ 0	$ 0
Transfer of assets from Level 2 to Level 1	0	0
Fair value transfers in or out of hierarchy level 3
Net transfer of liabilities into/out of level 3	$ 0	0
Convertible Notes
Estimated fair value of debt instruments
Interest rate (as a percent)	2.50%			2.50%
Par value of debt	$ 345,000			$ 345,000
Level 2 \| Convertible Notes \| Fair Value
Estimated fair value of debt instruments
Estimated fair value of debt	295,400
Contingent consideration \| Level 3
Changes in fair value of all financial liabilities measured at fair value on a recurring basis
Fair value, beginning of the period	14,825	14,971	$ 17,595
Divestiture of Lazanda	(3,515)
Total	1,613	14,825	14,971
Contingent consideration \| Level 3 \| Interest Expense.
Changes in fair value of all financial liabilities measured at fair value on a recurring basis
Net accretion value adjustments	1,079	2,408	2,307
Contingent consideration \| Level 3 \| Selling general and administrative expense
Changes in fair value of all financial liabilities measured at fair value on a recurring basis
Net accretion value adjustments	(7,708)	(122)	(3,684)
Contingent consideration \| Level 3 \| Royalties and milestone paid
Changes in fair value of all financial liabilities measured at fair value on a recurring basis
Net accretion value adjustments	$ 3,068	$ 2,432	$ 1,247