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LICENSE AND COLLABORATIVE ARRANGEMENTS (Details) - USD ($)
$ in Thousands
1 Months Ended 12 Months Ended
Mar. 31, 2014
Aug. 31, 2012
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
License arrangements          
Royalty revenue     $ 844 $ 831 $ 985
Mallinckrodt, Inc.          
License arrangements          
Milestone revenue recognized $ 1,000        
Janssen Pharmaceutica N.V.          
License arrangements          
Upfront fee received   $ 10,000      
Ironwood Pharmaceuticals, Inc.          
License arrangements          
Upfront fees, initial product formulation work and milestone payments received $ 3,400        
Milestone payment to be received if Ironwood commences with Phase 3 clinical trials     $ 5,000