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PROPERTY AND EQUIPMENT (Details) (USD $)
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Property and Equipment      
Property and equipment, gross $ 15,298,000us-gaap_PropertyPlantAndEquipmentGross $ 14,743,000us-gaap_PropertyPlantAndEquipmentGross  
Less: Accumulated depreciation and amortization (8,243,000)us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment (6,403,000)us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment  
Property and equipment, net 7,055,000us-gaap_PropertyPlantAndEquipmentNet 8,340,000us-gaap_PropertyPlantAndEquipmentNet  
Property and equipment under capitalized leases 0us-gaap_CapitalLeasesBalanceSheetAssetsByMajorClassNet 0us-gaap_CapitalLeasesBalanceSheetAssetsByMajorClassNet  
Depreciation expense 1,800,000us-gaap_Depreciation 1,600,000us-gaap_Depreciation 2,600,000us-gaap_Depreciation
Furniture and office equipment      
Property and Equipment      
Property and equipment, gross 4,097,000us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= depo_FurnitureAndOfficeEquipmentMember
3,547,000us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= depo_FurnitureAndOfficeEquipmentMember
 
Laboratory equipment      
Property and Equipment      
Property and equipment, gross 5,156,000us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_EquipmentMember
5,151,000us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_EquipmentMember
 
Leasehold improvements      
Property and Equipment      
Property and equipment, gross $ 6,045,000us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_LeaseholdImprovementsMember
$ 6,045,000us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_LeaseholdImprovementsMember