CONSOLIDATED BALANCE SHEETS (USD $) In Thousands, unless otherwise specified	Dec. 31, 2014	Dec. 31, 2013
Current assets:
Cash and cash equivalents	$ 488,668	$ 244,674
Marketable securities	70,773	27,263
Accounts receivable, net	27,008	11,451
Receivables from collaborative partners	1,070	10,824
Inventories	8,456	10,145
Income taxes receivable	4,030
Deferred tax assets, net	9,601	26,860
Prepaid and other current assets	8,014	5,828
Total current assets	617,620	337,045
Marketable securities, long-term	6,961	4,080
Property and equipment, net	7,055	8,340
Intangible assets, net	72,361	82,521
Deferred tax assets, net, non-current		76,342
Other assets	7,068	325
TOTAL ASSETS	711,065	508,653
Current liabilities:
Accounts payable and accrued liabilities	52,686	34,935
Income taxes payable		61,875
Deferred license revenue		3,041
Liability related to the sale of future royalties and milestones		56,357
Other current liabilities	4,813	649
Total current liabilities	57,499	156,857
Deferred license revenue, non-current portion		12,475
Contingent consideration liability	14,252	11,264
Liability related to the sale of future royalties and milestones, less current portion		177,624
Deferred tax liabilities, net, non-current	32,589
Convertible Debt	229,891
Other long-term liabilities	12,387	13,017
Commitments
Shareholders' equity:
Preferred stock, no par value, 5,000,000 shares authorized; Series A convertible preferred stock, 25,000 shares designated, 18,158 shares issued and surrendered, and zero shares outstanding at December 31, 2014 and December 31, 2013
Common stock, no par value, 100,000,000 shares authorized; 59,293,428 and 57,369,683 shares issued and outstanding at December 31, 2014 and December 31, 2013, respectively	239,961	221,124
Additional paid-in capital	76,809	347
Accumulated earnings (deficit)	47,714	(84,048)
Accumulated other comprehensive loss, net of tax	(37)	(7)
Total shareholders' equity	364,447	137,416
TOTAL LIABILITIES AND SHAREHOLDERS' EQUITY	$ 711,065	$ 508,653