CONSOLIDATED BALANCE SHEETS (USD $) In Thousands, unless otherwise specified	Dec. 31, 2013	Dec. 31, 2012
Current assets:
Cash and cash equivalents	$ 244,674	$ 29,076
Marketable securities	27,263	37,737
Accounts receivable	11,451	3,614
Receivables from collaborative partners	10,824	10,078
Inventories	10,145	9,587
Deferred tax assets, net	26,860
Prepaid and other current assets	5,828	5,175
Total current assets	337,045	95,267
Marketable securities, long-term	4,080	11,079
Property and equipment, net	8,340	8,237
Intangible assets, net	82,521	25,078
Deferred tax assets, net, non-current	76,342
Other assets	325	1,992
TOTAL ASSETS	508,653	141,653
Current liabilities:
Accounts payable and accrued liabilities	41,837	32,578
Income taxes payable	61,875
Deferred license revenue	3,041	3,273
Liability related to the sale of future royalties	49,455
Other current liabilities	649	830
Total current liabilities	156,857	36,681
Deferred license revenue, non-current portion	12,475	15,516
Contingent consideration liability	11,264	1,342
Liability related to the sale of future royalties, less current portion	177,624
Other long-term liabilities	13,017	4,178
Commitments
Shareholders' equity:
Preferred stock, no par value, 5,000,000 shares authorized; Series A convertible preferred stock, 25,000 shares designated, 18,158 shares issued and surrendered, and zero shares outstanding at December 31, 2013 and December 31, 2012
Common stock, no par value, 100,000,000 shares authorized; 57,369,683 and 56,383,713 shares issued and outstanding at December 31, 2013 and December 31, 2012, respectively	221,124	211,266
Additional paid-in capital	347
Accumulated deficit	(84,048)	(127,361)
Accumulated other comprehensive Income (loss), net of tax	(7)	31
Total shareholders' equity	137,416	83,936
TOTAL LIABILITIES AND SHAREHOLDERS' EQUITY	$ 508,653	$ 141,653