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LICENSE AND COLLABORATIVE ARRANGEMENTS - Narrative (Details) - USD ($)
3 Months Ended 12 Months Ended
Nov. 07, 2017
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Collaboration and License Agreements                        
Milestone payment recognized and collected   $ 42,599,000 $ 77,493,000 $ 63,274,000 $ 128,404,000 $ 94,407,000 $ 95,413,000 $ 100,457,000 $ 90,447,000 $ 311,770,000 $ 380,724,000 $ 455,897,000
Prepaid and other current assets   56,551,000       $ 17,238,000       56,551,000 17,238,000  
Research and development expenses                   8,042,000 13,718,000 $ 32,631,000
Slan | License Agreement                        
Collaboration and License Agreements                        
License agreement term 10 years                      
Commercialization efforts, amount $ 15,000,000                      
Prepaid and other current assets   $ 4,600,000               4,600,000    
Research and development expenses $ 24,900,000                 $ 2,250,000    
Ironwood Pharmaceuticals, Inc. | Milestone Payment                        
Collaboration and License Agreements                        
Milestone payment recognized and collected     $ 5,000,000 $ 5,000,000             $ 0