-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001285101-06-000002.txt : 20060421
<SEC-HEADER>0001285101-06-000002.hdr.sgml : 20060421
<ACCEPTANCE-DATETIME>20060421125231
ACCESSION NUMBER:		0001285101-06-000002
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20060421
FILED AS OF DATE:		20060421
DATE AS OF CHANGE:		20060421

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PHARMACEUTICAL PRODUCT DEVELOPMENT INC
		CENTRAL INDEX KEY:			0001003124
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH [8731]
		IRS NUMBER:				561640186
		STATE OF INCORPORATION:			NC
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		3151 SOUTH 17TH ST
		CITY:			WILMINGTON
		STATE:			NC
		ZIP:			28412
		BUSINESS PHONE:		9102510081

	MAIL ADDRESS:	
		STREET 1:		3151 SOUTH 17TH ST
		CITY:			WILMINGTON
		STATE:			NC
		ZIP:			28412

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SHANNON COLIN
		CENTRAL INDEX KEY:			0001285101

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-27570
		FILM NUMBER:		06771894

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		9102510081

	MAIL ADDRESS:	
		STREET 1:		3151 SOUTH 17TH ST.
		CITY:			WILMINGTON
		STATE:			NC
		ZIP:			28412
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>edgar.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2006-04-21</periodOfReport>

    <issuer>
        <issuerCik>0001003124</issuerCik>
        <issuerName>PHARMACEUTICAL PRODUCT DEVELOPMENT INC</issuerName>
        <issuerTradingSymbol>PPDI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001285101</rptOwnerCik>
            <rptOwnerName>SHANNON COLIN</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>216 GATEFIELD DRIVE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>WILMINGTON</rptOwnerCity>
            <rptOwnerState>NC</rptOwnerState>
            <rptOwnerZipCode>28412</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>EVP, Global Clinical Ops</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Stock Options (to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>14.22</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2006-02-13</value>
            </exerciseDate>
            <expirationDate>
                <value>2013-02-12</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>9000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>9000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Stock Options (to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>15.43</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2006-03-04</value>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2014-03-03</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>19334</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>19334</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Stock Options (to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>17.15</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2006-07-16</value>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <value>2014-07-15</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>40000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>40000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Stock Options (to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>21.19</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2005-11-16</value>
                <footnoteId id="F3"/>
            </exerciseDate>
            <expirationDate>
                <value>2014-11-15</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>130000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>130000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Stock Options (to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>34.62</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2007-02-22</value>
                <footnoteId id="F4"/>
            </exerciseDate>
            <expirationDate>
                <value>2016-02-21</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>40000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>40000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value></value>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">9,667 options are vested and exercisable as of 3/4/06; an additional 9,667 become vested and exercisable on 3/4/07.</footnote>
        <footnote id="F2">20,000 options are vested and execisable as of 7/16/06; an additional 20,000 become vested and exercisable on 7/16/07.</footnote>
        <footnote id="F3">This option was awarded on 11/16/04 and vests in four equal installments on 11/16/05, 11/16/06, 11/16/07 and 11/16/08.</footnote>
        <footnote id="F4">This option was awarded on 2/22/06 and vests in three equal installments on 2/22/07, 2/22/08 and 2/22/09.</footnote>
    </footnotes>

    <remarks>This report is being filed solely for informational purposes to reflect the Company's two-for-one stock split which was completed in February 2006.</remarks>

    <ownerSignature>
        <signatureName>Lisa C. Noecker attorney-in-fact for Colin Shannon</signatureName>
        <signatureDate>2006-04-21</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----