Cash And Cash Equivalents, Short-Term Investments, Long-Term Investments And Other Investments (Cash And Cash Equivalents, Short-Term Investments, Long-Term Investments And Other Investments) (Details) (USD $) In Thousands	Sep. 30, 2011	Dec. 31, 2010	Sep. 30, 2010	Dec. 31, 2009
Cash and Cash Equivalents	$ 416,746	$ 479,574	$ 440,442	$ 408,903
Short-term Investments	63,580	79,976
Long-term Investments		78,747
Other Investments	77,577	47,833
Unrealized Gains		345
Unrealized Losses		14,230
Cash [Member]
Cash and Cash Equivalents	197,077	246,843
Money Market Funds [Member]
Cash and Cash Equivalents	210,759	232,731
Certificates Of Deposit [Member]
Cash and Cash Equivalents	8,910
Municipal Debt Securities [Member]
Short-term Investments		32,707
Unrealized Gains		122
Unrealized Losses		24
Corporate Debt Securities [Member]
Short-term Investments		9,160
Unrealized Gains		105
Unrealized Losses		1
Auction Rate Securities [Member]
Short-term Investments	50,374
Long-term Investments		78,747
Unrealized Losses		14,203
Treasury Securities [Member]
Short-term Investments		38,109
Unrealized Gains		118
Unrealized Losses		2
Asset-Backed Securities [Member]
Short-term Investments	13,206
Celtic Therapeutics Holdings, L.P. [Member]
Other Investments	58,347	30,724
venBio Global Strategic Fund, L.P. [Member]
Other Investments	200
Bay City Capital Funds [Member]
Other Investments	8,751	7,069
A.M. Pappas Funds [Member]
Other Investments	3,546	3,486
Liquidia Technologies, Inc. [Member]
Other Investments	5,000	5,000
Other Investments [Member]
Other Investments	$ 1,733	$ 1,554