Exhibit 21
Pharmaceutical Product Development, Inc., and Subsidiaries
Subsidiaries
The subsidiaries of Pharmaceutical Product Development, Inc., as of February 2, 2004, are as follows:
| Name of Subsidiary |
Jurisdiction of Incorporation or Organized in | |||
| 1. | Applied Bioscience International Inc. | Delaware | ||
| 2. | Belmont Research, Inc. | Massachusetts | ||
| 3. | CSS Informatics, Inc. | California | ||
| 4. | Medical Research Laboratories International, LLC | Kentucky | ||
| 5. | Piedmont Research Center, Inc. | North Carolina | ||
| 6. | PPD Aeronautics, LLC | North Carolina | ||
| 7. | PPD Virtual, Inc. | North Carolina | ||
| 8. | APBI Finance Corporation | Delaware | ||
| 9. | APBI Holdings, LLC | North Carolina | ||
| 10. | Development Partners, LLC | Delaware | ||
| 11. | PPD GP, LLC | Delaware | ||
| 12. | PPD Holdings, LLC | Delaware | ||
| 13. | PPD UK Holdings Ltd. | United Kingdom | ||
| 14. | SARCO, LLC | Delaware | ||
| 15. | Genupro, Inc. | North Carolina | ||
| 16. | PPD Development, LP | Texas | ||
| 17. | ATP, LLC | North Carolina | ||
| 18. | Clinsights, Inc. | Delaware | ||
| 19. | Eminent Research Systems, Inc. | Delaware | ||
| 20. | Pharmaco Investments Inc. | Delaware | ||
| 21. | PPD International Holdings, Inc. | Delaware | ||
| 22. | PPD France SNC | France | ||
| 23. | PPD Scandinavia AB | Sweden | ||
| 24. | Pharmaceutical Product Development Spain SL | Spain | ||
| 25. | PPD do Brazil-Suporte a Pesquisa, LTDA | Brazil | ||
| 26. | PPD Argentina, SA | Argentina | ||
| 27. | PPD International Holdings, Inc. Y Compania Limitada | Chile | ||
| 28. | PPD South Africa | South Africa | ||
| 29. | PPD Canada, Ltd. | Canada | ||
| 30. | PPD Australia Pty Limited | Australia | ||
| 31. | PPD International Holdings GmbH | Germany | ||
| 32. | PPD Germany GmbH | Germany | ||
| 33. | PPD Poland Sp. Zo.O | Poland | ||
| 34. | PPD Czech Republic, S.r.o. | Czech Republic | ||
| 35. | PPD Germany GmbH & Co. KG | Germany | ||
| 36. | PPD Hungary R&D, Ltd. | Hungary | ||
| 37. | PPD Italy S.r.l | Italy | ||
| 38. | PPD Mexico S.A. de C.V. | Mexico | ||
| 39. | PPD Development (Thailand) Co., Ltd. | Thailand |
| 40. | PPD Japan, K.K. | Japan | ||
| 41. | PPD Global Ltd. | United Kingdom | ||
| 42. | Clinical Technology Centre International, Limited | United Kingdom | ||
| 43. | Cambridge Applied Nutrition Toxicology and Bioscience Limited | United Kingdom | ||
| 44. | Clinical Science Research International, Ltd. | United Kingdom | ||
| 45. | Leicester Clinical Research Centre, Ltd. | United Kingdom | ||
| 46. | Chelmsford Clinical Trials Unit, Ltd. | United Kingdom | ||
| 47. | Gabbay, Ltd. | United Kingdom | ||
| 48. | Data Analysis & Research, Ltd. | United Kingdom | ||
| 49. | Medical Research Laboratories International, BVBA | Belgium | ||
| 50. | PPD Development (S) Pte Ltd | Singapore | ||
| 51. | PPD Development (HK) Limited | Hong Kong | ||
| 52. | Propharma CRO Pty Ltd | Australia | ||
| 53. | PPD (Netherlands) B.V. | Netherlands |
Subsidiaries 1, 2, 3, 4, 5, 6 and 7 are wholly-owned subsidiaries of Pharmaceutical Product Development, Inc.
Subsidiaries 8, 9, 10, 11, 12, 13 and 14 are wholly-owned subsidiaries of Subsidiary 1.
Subsidiary 15 is a wholly-owned subsidiary of Subsidiary 7.
Subsidiary 16 is owned 99.9% by Subsidiary 12 and 0.1% by Subsidiary 11.
Subsidiaries 17, 18, 19, 20 and 21 are wholly-owned subsidiaries of Subsidiary 16.
Subsidiaries 23, 24, 25, 28, 29, 30, 31, 37, 39 and 40 are wholly-owned subsidiaries of Subsidiary 21.
Subsidiary 22 is owned 99.9% by Subsidiary 21 and 0.1% by Subsidiary 1.
Subsidiary 26 is owned 99.99% by Subsidiary 21 and 0.01% by Subsidiary 1.
Subsidiary 27 is owned 99% by Subsidiary 21 and 1% by Subsidiary 1.
Subsidiaries 32, 33 and 34 are wholly-owned subsidiaries of Subsidiary 31.
Subsidiary 35 is owned 72% by Subsidiary 31 and 28% by Subsidiary 32.
Subsidiary 36 is owned 96.7% by Subsidiary 31 and 3.3% by Subsidiary 21.
Subsidiary 38 is owned 99% by Subsidiary 21 and 1% by Subsidiary 16.
Subsidiaries 41, 45, 46, 47, 48, 50 and 53 are wholly-owned subsidiaries of Subsidiary 13.
Subsidiaries 42, 43 and 44 are wholly-owned subsidiaries of Subsidiary 41.
Subsidiary 49 is 99.9% owned by Subsidiary 13 and 0.1% by Subsidiary 41.
Subsidiary 51 is 50% owned by Subsidiary 50 and 50% by Subsidiary 1.
Subsidiary 52 is a wholly-owned subsidiary of Subsidiary 50.