Registered office, Piazzale Enrico Mattei, 1 00144 Roma Tel. +39 06 59821 eni.com

USSecurities and Exchange Commission

100 F Street, N.E.

Washington, DC 20549

United States of America

April 4, 2025

Re: Notice of disclosure pursuant to Section 2 19 of the Iran Threat Reduction and Syria Human Rights Act of 2012 and Section 13(r) of the Securities Exchange Act of 1934, as amended, included in Annual Report on Form 20-F for the year ended December 31, 2024 of Eni SpA.

Dear Sirs,

pursuant to Section 219 of the Iran Threat Reduction and Syria Human Rights Act of 2012 and Section 13(r) of the Securities Exchange Act of 1934, as amended, notice is hereby provided that Eni SpA has made disclosure pursuant to those provisions in its Annual Report on Form 20-F for the year ended December 31, 2024, which was filed with the Securities and Exchange Commission on April 4, 2025.

Sincerely,

/s/FRANCESCO ESPOSITO

Francesco Esposito

Title: Head of Accounting and Financial Statements

Eni SpA

Company share capital Euro 4,005,358,876.00 full paid up

Rome Company Register,

Tax Identification Number 00484960588

VAT number 00905811006,

R.E.A. Rome n. 756453

Branches:

Via Emilia, 1 and Piazza Ezio Vanoni, 1

20097 San Donato Milanese (Milan) - Italy