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QUARTERLY FINANCIAL INFORMATION (Details) - USD ($)
3 Months Ended 12 Months Ended
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Table Text Block Supplement [Abstract]                      
License revenue $ 38,095 $ 38,096 $ 38,095 $ 38,095 $ 38,095 $ 38,096 $ 38,095 $ 38,095      
Total costs and expenses 31,072,826 31,623,323 28,463,466 27,704,517 24,066,153 24,963,567 16,061,538 14,030,251 $ 118,864,132 $ 79,121,509 $ 63,332,397
Net loss $ (30,859,767) $ (31,535,652) $ (28,353,084) $ (27,727,509) $ (23,674,143) $ (24,831,027) $ (15,899,062) $ (13,848,662)      
Basic and diluted net loss per common share $ (0.46) $ (0.48) $ (0.45) $ (0.52) $ (0.48) $ (0.50) $ (0.33) $ (0.28) $ (1.91) $ (1.60) $ (1.38)