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Condensed Consolidated Statements of Cash Flows - USD ($)
9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (54,578,751) $ (45,336,834)
Adjustments to reconcile net loss to net cash used in operating activities:    
Gain on sale of long-term securities (33,042) 0
Noncash stock compensation expense 6,181,400 12,840,048
Depreciation 42,464 10,326
Amortization of premium on investment securities 367,673 377,770
Change in fair value of notes payable and accrued interest (63,822) (93,522)
Changes in assets and liabilities:    
Increase in restricted cash (3,041) (3,114)
Increase in prepaid research and development and other current assets (1,162,310) (4,055,116)
Increase in leasehold interest (2,517,771) 0
Decrease (increase) in accrued interest receivable 77,563 (73,011)
Increase in other assets (3,523) 0
Increase in accounts payable and accrued expenses 6,447,215 4,658,128
Increase in deferred rent 793,968 0
Decrease in deferred revenue (114,286) (114,286)
Net cash used in operating activities (44,566,263) (31,789,611)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Purchases of equipment (323,015) (59,194)
Investment in held-to-maturity securities (15,199,922) (40,955,137)
Proceeds from maturity of short-term securities 18,000,000 13,850,000
Proceeds from sale of long-term securities 12,589,219 0
Net cash provided by (used in) investing activities 15,066,282 (27,164,331)
CASH FLOWS FROM FINANCING ACTIVITIES:    
Proceeds from the exercise of warrants 100,896 1,009,985
Proceeds from sale of common stock, net 3,504,261 67,760,517
Financing costs (9,984) (68,404)
Net cash provided by financing activities 3,595,173 68,702,098
NET (DECREASE) INCREASE IN CASH AND CASH EQUIVALENTS (25,904,808) 9,748,156
CASH AND CASH EQUIVALENTS AT BEGINNING OF PERIOD 55,061,329 55,713,784
CASH AND CASH EQUIVALENTS AT END OF PERIOD 29,156,521 65,461,940
NONCASH TRANSACTIONS    
Reclassification of deferred financing costs to additional paid-in capital (56,988) (63,788)
Conversion of convertible notes payable to common stock $ 30,601 $ 0