ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Details Narrative) - USD ($)	6 Months Ended		12 Months Ended
	Jun. 30, 2016	Jun. 30, 2015	Dec. 31, 2015
Accounting Policies [Abstract]
Accumulated deficit	$ (187,881,650)		$ (158,133,926)
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount	6,449,737	5,668,134
Period Anticipated Sufficient To Fund Operating Cash Flow	18 to 24 months	18 to 24 months	18 to 24 months
Cash, Cash Equivalents, and Short-term Investments, Total	$ 75,800,000
Restricted Cash and Investments	600,000
Prepaid Manufacturing	$ 14,500,000		$ 9,200,000