Condensed Consolidated Statements of Cash Flows (Parenthetical) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Reconciliation to amounts on consolidated balance sheets:
Cash and cash equivalents	$ 298,887	$ 553,439	$ 112,637
Restricted cash	1,264	1,259	1,251
Total cash, cash equivalents and restricted cash	300,151	554,698	113,888
Cash paid for:
Interest	3,466	4,501	2,622
NONCASH TRANSACTIONS
Deferred financing costs	4,165	0	988
Warrants issued with debt financing	2,196	0	993
Shares issued in connection with in-licensing	$ 0	$ 0	$ 100