Condensed Consolidated Statements of Operations - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Revenue:
Total revenue	$ 6,689	$ 152	$ 152
Costs and expenses:
Cost of product revenue	790	0
Research and development:
Noncash stock expense associated with in-licensing agreements		0	100
Noncash compensation	24,047	13,962	5,811
Other research and development	198,532	151,934	148,269
Total research and development	222,579	165,896	154,180
Selling, general and administrative:
Noncash compensation	37,227	66,327	5,523
Other selling, general and administrative	90,863	41,523	9,504
Total selling, general and administrative	128,090	107,850	15,027
Total costs and expenses	351,459	273,746	169,207
Operating loss	(344,770)	(273,594)	(169,055)
Other expense (income):
Interest expense	5,638	6,329	5,287
Other income	(2,307)	(542)	(1,471)
Total other expense (income), net	3,331	5,787	3,816
Net loss	$ (348,101)	$ (279,381)	$ (172,871)
Basic and diluted net loss per common share (in dollars per share)	$ (2.63)	$ (2.42)	$ (1.96)
Weighted average shares used in computing basic and diluted net loss per common share (in shares)	132,222,753	115,333,693	88,368,844
Product revenue, net [Member]
Revenue:
Total revenue	$ 6,537	$ 0
License revenue [Member]
Revenue:
Total revenue	$ 152	$ 152	$ 152